Product Name :
Na+/K+ ATPase Mouse Monoclonal Antibody [1G1]
Predicted band size :
Observed band size :
Synonyms:
A1A1 antibody AT1A1 antibody AT1A1_HUMAN antibody ATP1A1 antibody Atpa-1 antibody ATPase Na+/K+ transporting alpha 1 polypeptide antibody ATPase Na+/K+ transporting subunit alpha 1 antibody BC010319 antibody EC 3.6.3.9 antibody MGC3285 antibody 展开
Function :
The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.2409005-96-3 manufacturer
Antibody Type:
Mouse Monoclonal Antibody
Immunogen :
Amino acids 551-850 of Na+/K+-ATPase α1 of human origin.1310680-47-7 Chemscene
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IP, IF, IHC-P
Coupling :
unconjugated
Clone number:
1G1
RRID:
Form :
Liquid
Concentration :
2ug/ul
Storage instructions:
Store at +4℃
Storage buffer solution:
1.PMID:33719834 0 ml of PBS with
Subtype:
IgG1
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
100-143kDa
Positive control :
Hela, human duodenum tissue, human kidney tissue, human brain tissue.