Product Name :
NrCAM Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Bravo antibody hBravo antibody Neuronal cell adhesion molecule antibody Neuronal surface protein Bravo antibody Ng CAM related antibody Ng-CAM-related antibody NgCAM related cell adhesion molecule antibody NgCAM-related cell adhesion molecule antibody Nr CAM antibody Nr-CAM antibody 展开
Function :
Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Recombinant protein within Human NRCAM aa 723-903 / 1,304.
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3069259
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Fmoc-Lys-OH (hydrochloride) Price Aliquot store at -20℃.156311-83-0 custom synthesis Avoid repeated freeze / thaw cycles.PMID:33588646
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 144 kDa
Positive control :
SH-SY5Y cell lysate, A549, SH-SY5Y, SKOV-3, rat brain tissue, mouse brain tissue.